منابع مشابه
Pág. 475-
mammalian CNS, the actions of which are regulated by ionotropic glutamate (iGlu) and metabotropic glutamate receptors (mGlu). mGlu receptors are a family of G-protein-coupled receptors comprising eight members, refered to as mGlu1-8. Group I receptors include mGlu1 and mGlu5, which when expressed are coupled via Gq to phospholipase C. Group II (mGlu2 and mGlu3) and group III (mGlu4,6,7,8) recep...
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Positive allosteric modulators (PAMs) of a7 nicotinic acetylcholine receptors can enhance ion channel currents and downstream effects of a7 stimulation. We investigated the approach of using noncompetitive antagonists to regulate a7 receptor function, potentially distinguishing effects requiring ion channel currents from signaling induced by nonconducting states. Three small readily reversible ...
متن کاملDmd048561 475..479
This study was designed to evaluate the in vivo activity of cytochrome P450 3A (CYP3A) in 49 healthy Japanese subjects aged 22–58 years using endogenous cortisol 6b-hydroxylation clearance [CLm(6b)], a novel biomarker for CYP3A phenotyping. CLm(6b) in the 49 healthy subjects was 2.40 6 0.79 ml/min with an approximately 4fold interindividual variability of CYP3A activity. The mean clearance in t...
متن کاملHN 534_Vorwort.fm
Von Beethovens Liedern gab es bisher nur zwei für die musikalische Praxis bestimmte Ausgaben. Beide sind Nachdrucke der ersten Gesamtausgabe (GA). Sie stimmen daher im Notentext, im Inhalt und sogar in der Reihenfolge der Kompositionen miteinander überein. Beide enthalten jedoch lediglich die im Liederband der GA (1864) erschienenen Stücke. Es fehlen selbst diejenigen Kompositionen, die bald na...
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S M T A s m s s n b p m m is now a postdoctoral research as Science and Engineering Departm University, and working to devel adhesives by integrating carbon na Center of Advanced Science and Engineerin of Macromolecular Science and Engineering, Reserve University, 10900 Euclid Avenue, Cle [email protected] Department of Materials Science and E University of North Texas, Denton, TX 7620 Cite this: Na...
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ژورنال
عنوان ژورنال: Astronomische Nachrichten
سال: 1902
ISSN: 0004-6337,1521-3994
DOI: 10.1002/asna.19021590806